Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target
نویسندگان
چکیده
منابع مشابه
Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target
Heat shock protein 27 (HSP27) is a multidimensional protein which acts as a protein chaperone and an antioxidant and plays a role in the inhibition of apoptosis and actin cytoskeletal remodeling. In each of these capacities, HSP27 has been implicated in different disease states playing both protective and counter-protective roles. The current review presents HSP27 in multiple disease contexts: ...
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Heat shock proteins (HSPs), known as molecular chaperone to assist protein folding, have recently become a research focus in Parkinson's disease (PD) because the pathogenesis of this disease is highlighted by the intracellular protein misfolding and inclusion body formation. The present review will focus on the functions of different HSPs and their protective roles in PD. It is postulated that ...
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ژورنال
عنوان ژورنال: Fibrogenesis & Tissue Repair
سال: 2012
ISSN: 1755-1536
DOI: 10.1186/1755-1536-5-7